Prototype. Structures and fluorescent-protein spectra are real public data. Stability parameters, mutation effects and instrument readings are synthetic.Prototype. Real structures and spectra; synthetic stability and instrument.
MDT
Structure and temperature in.Energy and light out.Kept true by measurement.
A digital twin of a single biomolecule. Scroll to travel from the cuvette to the electrons.
Field of view
Time scale
Stability dG unfold vs temperatureMelting energy vs spectral readoutSpectrumResidues predicted alanine-scan dG change, 80 percent bandLearning error against synthetic truth